Cargando…

A promising platform for predicting toxicity

Organ-on-chip approaches could help researchers to better predict the toxicity of cancer immunotherapy drugs.

Detalles Bibliográficos
Autor principal:	Ochoa de Olza, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463070/ https://www.ncbi.nlm.nih.gov/pubmed/34558412 http://dx.doi.org/10.7554/eLife.73191

Ejemplares similares

Tris–base buffer: a promising new inhibitor for cancer progression and metastasis
por: Ibrahim‐Hashim, Arig, et al.
Publicado: (2017)

Tissue-derived exosome proteomics identifies promising diagnostic biomarkers for esophageal cancer
por: Rao, Dingyu, et al.
Publicado: (2023)

Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma
por: Nakai, Takaaki, et al.
Publicado: (2017)

HOXA11 antisense long noncoding RNA (HOXA11‐AS): A promising lncRNA in human cancers
por: Lu, Cheng‐Wei, et al.
Publicado: (2018)

EPAC1 inhibition protects the heart from doxorubicin-induced toxicity
por: Mazevet, Marianne, et al.
Publicado: (2023)

CD95/Fas ligand mRNA is toxic to cells
por: Putzbach, Will, et al.
Publicado: (2018)

A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes
por: Carrami, Eli M, et al.
Publicado: (2020)

Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies
por: Kerns, S Jordan, et al.
Publicado: (2021)

Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy
por: Chen, Leying, et al.
Publicado: (2022)

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells
por: Unni, Arun M, et al.
Publicado: (2018)

ALOX5‐5‐HETE promotes gastric cancer growth and alleviates chemotherapy toxicity via MEK/ERK activation
por: Tang, Jianjun, et al.
Publicado: (2021)

Establishment of patient‐derived xenograft model of peritoneal mucinous carcinomatosis with signet ring cells and in vivo study on the efficacy and toxicity of intraperitoneal injection of 5‐fluorouracil
por: Lin, Yu‐Lin, et al.
Publicado: (2019)

Mixed outcomes for computational predictions
por: Dang, Chi Van
Publicado: (2017)

Improving survival prediction for melanoma
por: Artomov, Mykyta
Publicado: (2019)

EORTC SPECTA‐AYA: A unique molecular profiling platform for adolescents and young adults with cancer in Europe
por: de Rojas, Teresa, et al.
Publicado: (2019)

Predicting cancer risk based on family history
por: Jacobs, Michelle F
Publicado: (2021)

MGMT autoantibodies as a potential prediction of recurrence and treatment response biomarker for glioma patients
por: Wu, Haibin, et al.
Publicado: (2019)

An immune‐related prognostic signature for predicting breast cancer recurrence
por: Tian, Zelin, et al.
Publicado: (2020)

Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction
por: Wang, Shixiang, et al.
Publicado: (2019)

Improving the overall survival prognosis prediction accuracy: A 9‐gene signature in CRC patients
por: Zheng, Wenbo, et al.
Publicado: (2021)

LC3A‐Positive “Stone‐Like” Structures Predict an Adverse Prognosis of Gastric Cancer
por: Liao, Wenjun, et al.
Publicado: (2014)

Establishment of a nine‐gene prognostic model for predicting overall survival of patients with endometrial carcinoma
por: Ying, Jianchao, et al.
Publicado: (2018)

A signature of 33 immune‐related gene pairs predicts clinical outcome in hepatocellular carcinoma
por: Sun, Xiao‐Yan, et al.
Publicado: (2020)

Immune‐related signature predicts the prognosis and immunotherapy benefit in bladder cancer
por: Wang, Yejinpeng, et al.
Publicado: (2020)

Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
por: Rodriguez, Jonathan, et al.
Publicado: (2023)

NOTCH3 limits the epithelial–mesenchymal transition and predicts a favorable clinical outcome in esophageal cancer
por: Matsuura, Norihiro, et al.
Publicado: (2021)

A four‐gene signature associated with clinical features can better predict prognosis in prostate cancer
por: Yuan, Penghui, et al.
Publicado: (2020)

Uridine phosphorylase 1 is a novel immune‐related target and predicts worse survival in brain glioma
por: Wang, Jin, et al.
Publicado: (2020)

Development of an IFNγ response‐related signature for predicting the survival of cutaneous melanoma
por: Hu, Baohui, et al.
Publicado: (2020)

FABP4 suppresses proliferation and invasion of hepatocellular carcinoma cells and predicts a poor prognosis for hepatocellular carcinoma
por: Zhong, Cheng‐Qian, et al.
Publicado: (2018)

Genomewide identification of a novel six‐LncRNA signature to improve prognosis prediction in resectable hepatocellular carcinoma
por: Wu, Ying, et al.
Publicado: (2018)

Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma
por: Christensen, Brock C., et al.
Publicado: (2008)

Aberrant CpG‐methylation affects genes expression predicting survival in lung adenocarcinoma
por: He, Wei, et al.
Publicado: (2018)

Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
por: Umu, Sinan U, et al.
Publicado: (2022)

Jupiter microtubule‐associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers
por: Bateman, Nicholas W., et al.
Publicado: (2019)

Signature based on metabolic‐related gene pairs can predict overall survival of osteosarcoma patients
por: Li, Long‐Qing, et al.
Publicado: (2021)

GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome
por: Zhou, Jing‐Dong, et al.
Publicado: (2016)

Nuclear division cycle 80 promotes malignant progression and predicts clinical outcome in colorectal cancer
por: Yan, Xuebing, et al.
Publicado: (2018)

CTHRC1 overexpression predicts poor survival and enhances epithelial‐mesenchymal transition in colorectal cancer
por: Ni, Shujuan, et al.
Publicado: (2018)

Is preoperative serum lactate dehydrogenase useful in predicting the outcomes of patients with upper tract urothelial carcinoma?
por: Tan, Ping, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nfjei5btbpnhlbfk2c87lqbuep