Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

BACKGROUND: SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. METHODS: We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model...

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Detalles Bibliográficos
Autores principales: Tindle, Courtney, Fuller, MacKenzie, Fonseca, Ayden, Taheri, Sahar, Ibeawuchi, Stella-Rita, Beutler, Nathan, Katkar, Gajanan Dattatray, Claire, Amanraj, Castillo, Vanessa, Hernandez, Moises, Russo, Hana, Duran, Jason, Crotty Alexander, Laura E, Tipps, Ann, Lin, Grace, Thistlethwaite, Patricia A, Chattopadhyay, Ranajoy, Rogers, Thomas F, Sahoo, Debashis, Ghosh, Pradipta, Das, Soumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463074/
https://www.ncbi.nlm.nih.gov/pubmed/34463615
http://dx.doi.org/10.7554/eLife.66417

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