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An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse agonist of CXCR4 and is a promising compound for t...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463264/ https://www.ncbi.nlm.nih.gov/pubmed/34589390 http://dx.doi.org/10.1016/j.apsb.2020.12.005 |