An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse agonist of CXCR4 and is a promising compound for t...

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Detalles Bibliográficos
Autores principales: Harms, Mirja, Habib, Monica M.W., Nemska, Simona, Nicolò, Antonella, Gilg, Andrea, Preising, Nico, Sokkar, Pandian, Carmignani, Sara, Raasholm, Martina, Weidinger, Gilbert, Kizilsavas, Gönül, Wagner, Manfred, Ständker, Ludger, Abadi, Ashraf H., Jumaa, Hassan, Kirchhoff, Frank, Frossard, Nelly, Sanchez-Garcia, Elsa, Münch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463264/
https://www.ncbi.nlm.nih.gov/pubmed/34589390
http://dx.doi.org/10.1016/j.apsb.2020.12.005

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