Tryptophan 2,3-dioxygenase 2 controls M2 macrophages polarization to promote esophageal squamous cell carcinoma progression via AKT/GSK3β/IL-8 signaling pathway

Tryptophan 2,3-dioxygnease 2 (TDO2) is specific for metabolizing tryptophan to kynurenine (KYN), which plays a critical role in mediating immune escape of cancer. Although accumulating evidence demonstrates that TDO2 overexpression is implicated in the development and progression of multiple cancers...

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Detalles Bibliográficos
Autores principales: Zhao, Yumiao, Sun, Jiaxin, Li, Yin, Zhou, Xiuman, Zhai, Wenjie, Wu, Yahong, Chen, Guanyu, Gou, Shanshan, Sui, Xinghua, Zhao, Wenshan, Qiu, Lu, Yao, Yongjie, Sun, Yixuan, Chen, Chunxia, Qi, Yuanming, Gao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463272/
https://www.ncbi.nlm.nih.gov/pubmed/34589400
http://dx.doi.org/10.1016/j.apsb.2021.03.009

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