High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines

Although both infections and vaccines induce memory B cell (MBC) populations that participate in secondary immune responses, the MBCs generated in each case can differ. Here, we compare SARS-CoV-2 spike receptor binding domain (S1-RBD)-specific primary MBCs that form in response to infection or a si...

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Detalles Bibliográficos
Autores principales: Pape, Kathryn A., Dileepan, Thamotharampillai, Kabage, Amanda J., Kozysa, Daria, Batres, Rodolfo, Evert, Clayton, Matson, Michael, Lopez, Sharon, Krueger, Peter D., Graiziger, Carolyn, Vaughn, Byron P., Shmidt, Eugenia, Rhein, Joshua, Schacker, Timothy W., Khoruts, Alexander, Jenkins, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463313/
https://www.ncbi.nlm.nih.gov/pubmed/34610291
http://dx.doi.org/10.1016/j.celrep.2021.109823

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