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New strategies for managing adult gliomas
Gliomas are hard to treat. Their prognosis has improved little over the past few decades. Fundamental therapeutic challenges such as treatment resistance, malignant progression, and tumour recurrence persist. New strategies are needed to advance the management and treatment of gliomas. Here, we focu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463358/ https://www.ncbi.nlm.nih.gov/pubmed/32542524 http://dx.doi.org/10.1007/s00415-020-09884-3 |
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author | Kirby, Alastair J. Finnerty, Gerald T. |
author_facet | Kirby, Alastair J. Finnerty, Gerald T. |
author_sort | Kirby, Alastair J. |
collection | PubMed |
description | Gliomas are hard to treat. Their prognosis has improved little over the past few decades. Fundamental therapeutic challenges such as treatment resistance, malignant progression, and tumour recurrence persist. New strategies are needed to advance the management and treatment of gliomas. Here, we focus on where those new strategies could emerge. We consider how recent advances in our understanding of the biology of adult gliomas are informing new approaches to their treatment. |
format | Online Article Text |
id | pubmed-8463358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-84633582021-10-08 New strategies for managing adult gliomas Kirby, Alastair J. Finnerty, Gerald T. J Neurol Review Gliomas are hard to treat. Their prognosis has improved little over the past few decades. Fundamental therapeutic challenges such as treatment resistance, malignant progression, and tumour recurrence persist. New strategies are needed to advance the management and treatment of gliomas. Here, we focus on where those new strategies could emerge. We consider how recent advances in our understanding of the biology of adult gliomas are informing new approaches to their treatment. Springer Berlin Heidelberg 2020-06-15 2021 /pmc/articles/PMC8463358/ /pubmed/32542524 http://dx.doi.org/10.1007/s00415-020-09884-3 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Kirby, Alastair J. Finnerty, Gerald T. New strategies for managing adult gliomas |
title | New strategies for managing adult gliomas |
title_full | New strategies for managing adult gliomas |
title_fullStr | New strategies for managing adult gliomas |
title_full_unstemmed | New strategies for managing adult gliomas |
title_short | New strategies for managing adult gliomas |
title_sort | new strategies for managing adult gliomas |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463358/ https://www.ncbi.nlm.nih.gov/pubmed/32542524 http://dx.doi.org/10.1007/s00415-020-09884-3 |
work_keys_str_mv | AT kirbyalastairj newstrategiesformanagingadultgliomas AT finnertygeraldt newstrategiesformanagingadultgliomas |