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Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury

RNA interference-based gene silencing drugs are attracting attention for treating various diseases. Lipid nanoparticles (LNPs) are carriers that efficiently deliver small interfering RNA (siRNA) to the cytoplasm of target cells. Recently, we developed potent and well-tolerated biodegradable LNPs wit...

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Detalles Bibliográficos
Autores principales:	Kawase, Wataru, Kurotaki, Daisuke, Suzuki, Yuta, Ishihara, Hiroshi, Ban, Tatsuma, Sato, Go R., Ichikawa, Juri, Yanai, Hideyuki, Taniguchi, Tadatsugu, Tsukahara, Kappei, Tamura, Tomohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463440/ https://www.ncbi.nlm.nih.gov/pubmed/34589288 http://dx.doi.org/10.1016/j.omtn.2021.08.023

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