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Synthesis, in vivo and in silico analgesic and anti-inflammatory studies of α-D-ribofuranose derivatives

Five α-D-ribofuranose analogues (2, 3, 4, 5 and 6) were synthesized in good yields from 3-O-benzyl-4-C-(hydroxymethyl)-1, 2-O-isopropylidene-α-D-ribofuranose (1). The synthesized compounds were then subjected to analgesic, anti-inflammatory, antimicrobial and antioxidant assays. Compound 3 demonstra...

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Detalles Bibliográficos
Autores principales: Spriha, Sabiha Enam, Rahman, Fahad Imtiaz, Rahman, S. M. Abdur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463446/
https://www.ncbi.nlm.nih.gov/pubmed/34588844
http://dx.doi.org/10.1016/j.jsps.2021.07.017

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