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High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients

OBJECTIVE: To determine the prevalence of low vitamin D (<30 ng/mL), including vitamin D insufficiency (20-29.9 ng/mL) and deficiency (<20 ng/mL), in an acute rehabilitation setting. DESIGN: Cross-sectional, retrospective cohort study. SETTING: University-affiliated inpatient rehabilitation fa...

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Autores principales: Wu, Jennifer, Chavez-Arom, Valerie, Han, Jay J., Yeh, Bi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463507/
https://www.ncbi.nlm.nih.gov/pubmed/34589687
http://dx.doi.org/10.1016/j.arrct.2021.100137
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author Wu, Jennifer
Chavez-Arom, Valerie
Han, Jay J.
Yeh, Bi-Ying
author_facet Wu, Jennifer
Chavez-Arom, Valerie
Han, Jay J.
Yeh, Bi-Ying
author_sort Wu, Jennifer
collection PubMed
description OBJECTIVE: To determine the prevalence of low vitamin D (<30 ng/mL), including vitamin D insufficiency (20-29.9 ng/mL) and deficiency (<20 ng/mL), in an acute rehabilitation setting. DESIGN: Cross-sectional, retrospective cohort study. SETTING: University-affiliated inpatient rehabilitation facility (IRF) at a metropolitan county hospital. PARTICIPANTS: Patients (N=100; 64 men/36 women), aged 19-92 years (mean, 62±18.9y), who were admitted to and discharged from an IRF over a 6-month study period. The most frequent admitting diagnoses included stroke (n=11), brain injury (n=36), spinal cord injury (n=14), and polytrauma (n=10). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Serum vitamin-25 (OH)D level at admission to the IRF. RESULTS: Of 100 patients, 76% had low vitamin D (<30 ng/mL), with 29% demonstrating vitamin D insufficiency (20-29.9 ng/mL) and 47% demonstrating vitamin D deficiency (<20 ng/mL). Younger patients demonstrated higher rates of vitamin D deficiency compared with older patients (P<.0001). CONCLUSIONS: Low vitamin D is common in patients admitted to the IRF, with rates more than double those reported in the general population among individuals younger than 45 years. The current results suggest that the IRF setting may be a favorable checkpoint to screen for and initiate treatment of low vitamin D and optimize rehabilitation outcomes.
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spelling pubmed-84635072021-09-28 High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients Wu, Jennifer Chavez-Arom, Valerie Han, Jay J. Yeh, Bi-Ying Arch Rehabil Res Clin Transl Original Research OBJECTIVE: To determine the prevalence of low vitamin D (<30 ng/mL), including vitamin D insufficiency (20-29.9 ng/mL) and deficiency (<20 ng/mL), in an acute rehabilitation setting. DESIGN: Cross-sectional, retrospective cohort study. SETTING: University-affiliated inpatient rehabilitation facility (IRF) at a metropolitan county hospital. PARTICIPANTS: Patients (N=100; 64 men/36 women), aged 19-92 years (mean, 62±18.9y), who were admitted to and discharged from an IRF over a 6-month study period. The most frequent admitting diagnoses included stroke (n=11), brain injury (n=36), spinal cord injury (n=14), and polytrauma (n=10). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Serum vitamin-25 (OH)D level at admission to the IRF. RESULTS: Of 100 patients, 76% had low vitamin D (<30 ng/mL), with 29% demonstrating vitamin D insufficiency (20-29.9 ng/mL) and 47% demonstrating vitamin D deficiency (<20 ng/mL). Younger patients demonstrated higher rates of vitamin D deficiency compared with older patients (P<.0001). CONCLUSIONS: Low vitamin D is common in patients admitted to the IRF, with rates more than double those reported in the general population among individuals younger than 45 years. The current results suggest that the IRF setting may be a favorable checkpoint to screen for and initiate treatment of low vitamin D and optimize rehabilitation outcomes. Elsevier 2021-06-30 /pmc/articles/PMC8463507/ /pubmed/34589687 http://dx.doi.org/10.1016/j.arrct.2021.100137 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Wu, Jennifer
Chavez-Arom, Valerie
Han, Jay J.
Yeh, Bi-Ying
High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title_full High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title_fullStr High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title_full_unstemmed High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title_short High Rates of Vitamin D Deficiency in Acute Rehabilitation Patients
title_sort high rates of vitamin d deficiency in acute rehabilitation patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463507/
https://www.ncbi.nlm.nih.gov/pubmed/34589687
http://dx.doi.org/10.1016/j.arrct.2021.100137
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