Cardiac radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis

Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with refractory ventricular tachycardia (VT). The previously proposed mechanism of radiation-induced fibrosis does not explain the rapidity and magnitude with which VT reduction occurs clinically. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Zhang, David M., Navara, Rachita, Yin, Tiankai, Szymanski, Jeffrey, Goldsztejn, Uri, Kenkel, Camryn, Lang, Adam, Mpoy, Cedric, Lipovsky, Catherine E., Qiao, Yun, Hicks, Stephanie, Li, Gang, Moore, Kaitlin M. S., Bergom, Carmen, Rogers, Buck E., Robinson, Clifford G., Cuculich, Phillip S., Schwarz, Julie K., Rentschler, Stacey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463558/
https://www.ncbi.nlm.nih.gov/pubmed/34561429
http://dx.doi.org/10.1038/s41467-021-25730-0

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