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Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers

Hairy cell leukaemia (HCL) is a rare CD20+ B cell malignancy characterised by rare “hairy” B cells and extensive bone marrow (BM) infiltration. Frontline treatment with the purine analogue cladribine (CDA) results in a highly variable response duration. We hypothesised that analysis of the BM tumour...

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Detalles Bibliográficos
Autores principales: Koldej, Rachel M., Prabahran, Ashvind, Tan, Chin Wee, Ng, Ashley P., Davis, Melissa J., Ritchie, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463612/
https://www.ncbi.nlm.nih.gov/pubmed/34561502
http://dx.doi.org/10.1038/s41598-021-98536-1

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