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Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers
Hairy cell leukaemia (HCL) is a rare CD20+ B cell malignancy characterised by rare “hairy” B cells and extensive bone marrow (BM) infiltration. Frontline treatment with the purine analogue cladribine (CDA) results in a highly variable response duration. We hypothesised that analysis of the BM tumour...
Autores principales: | Koldej, Rachel M., Prabahran, Ashvind, Tan, Chin Wee, Ng, Ashley P., Davis, Melissa J., Ritchie, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463612/ https://www.ncbi.nlm.nih.gov/pubmed/34561502 http://dx.doi.org/10.1038/s41598-021-98536-1 |
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