Mitochondrial augmentation of CD34(+) cells from healthy donors and patients with mitochondrial DNA disorders confers functional benefit

Mitochondria are cellular organelles critical for numerous cellular processes and harboring their own circular mitochondrial DNA (mtDNA). Most mtDNA associated disorders (either deletions, mutations, or depletion) lead to multisystemic disease, often severe at a young age, with no disease-modifying...

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Detalles Bibliográficos
Autores principales: Jacoby, Elad, Ben Yakir-Blumkin, Moriya, Blumenfeld-Kan, Shiri, Brody, Yehuda, Meir, Amilia, Melamed-Book, Naomi, Napso, Tina, Pozner, Gat, Saadi, Esraa, Shabtay-Orbach, Ayelet, Yivgi-Ohana, Natalie, Sher, Noa, Toren, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463667/
https://www.ncbi.nlm.nih.gov/pubmed/34561447
http://dx.doi.org/10.1038/s41536-021-00167-7

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