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Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features

Olfactory loss, motor impairment, anxiety/depression, and REM-sleep behaviour disorder (RBD) are prodromal Parkinson’s disease (PD) features. PD risk prediction models typically dichotomize test results and apply likelihood ratios (LRs) to scores above and below cut-offs. We investigate whether LRs...

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Detalles Bibliográficos
Autores principales: Bestwick, Jonathan P., Auger, Stephen D., Schrag, Anette E., Grosset, Donald G., Kanavou, Sofia, Giovannoni, Gavin, Lees, Andrew J., Cuzick, Jack, Noyce, Alastair J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463675/
https://www.ncbi.nlm.nih.gov/pubmed/34561458
http://dx.doi.org/10.1038/s41531-021-00226-2