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The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients

The present study aimed to describe the blood pressure (BP) control rate and 10-years arteriosclerotic cardiovascular disease (ASCVD) risk estimation among community hypertensive patients. A total of 196,803 subjects were enrolled. The control rates calculated as the intensive (SBP < 130 mmHg and...

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Autores principales: Liu, Shijun, Yuan, Hanyan, Jiang, Caixia, Xu, Jue, Qiu, Xin, Luo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463712/
https://www.ncbi.nlm.nih.gov/pubmed/34561523
http://dx.doi.org/10.1038/s41598-021-98745-8
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author Liu, Shijun
Yuan, Hanyan
Jiang, Caixia
Xu, Jue
Qiu, Xin
Luo, Jun
author_facet Liu, Shijun
Yuan, Hanyan
Jiang, Caixia
Xu, Jue
Qiu, Xin
Luo, Jun
author_sort Liu, Shijun
collection PubMed
description The present study aimed to describe the blood pressure (BP) control rate and 10-years arteriosclerotic cardiovascular disease (ASCVD) risk estimation among community hypertensive patients. A total of 196,803 subjects were enrolled. The control rates calculated as the intensive (SBP < 130 mmHg and DBP < 80 mmHg) and standard (SBP < 140 mmHg and DBP < 90 mmHg) threshold. Multivariable logistic analysis was employed to assess the associations between cardiovascular factors and BP control. Sensitivity, specificity and Youden’s index were used to identify the ability of high risk of ASCVD estimation by different thresholds. The control rate was 16.34% and 50.25% by the intensive and standard threshold, respectively. Besides regular medication, the risk factors for BP control included older age, male, unhealthy lifestyle, obesity, dyslipidemia and abnormal FPG. 25.08% of subjects had high risk of 10-years ASCVD estimation. The sensitivity, specificity and Youden’s index of intensive threshold was 84.37%, 16.15% and 0.51%, and were significantly different from 50.55%, 50.42% and 0.98% of the standard threshold, respectively. Half of community hypertensive patients did not control BP, and nearly a quarter have high risk of 10-years ASCVD risk estimation. The intensive threshold resulted in a one-third reduction in the control rate compared to the standard threshold. No matter which threshold was used, a single BP control status seemed not a suitable indicator for identification of high risk of 10-years ASCVD risk estimation.
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spelling pubmed-84637122021-09-29 The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients Liu, Shijun Yuan, Hanyan Jiang, Caixia Xu, Jue Qiu, Xin Luo, Jun Sci Rep Article The present study aimed to describe the blood pressure (BP) control rate and 10-years arteriosclerotic cardiovascular disease (ASCVD) risk estimation among community hypertensive patients. A total of 196,803 subjects were enrolled. The control rates calculated as the intensive (SBP < 130 mmHg and DBP < 80 mmHg) and standard (SBP < 140 mmHg and DBP < 90 mmHg) threshold. Multivariable logistic analysis was employed to assess the associations between cardiovascular factors and BP control. Sensitivity, specificity and Youden’s index were used to identify the ability of high risk of ASCVD estimation by different thresholds. The control rate was 16.34% and 50.25% by the intensive and standard threshold, respectively. Besides regular medication, the risk factors for BP control included older age, male, unhealthy lifestyle, obesity, dyslipidemia and abnormal FPG. 25.08% of subjects had high risk of 10-years ASCVD estimation. The sensitivity, specificity and Youden’s index of intensive threshold was 84.37%, 16.15% and 0.51%, and were significantly different from 50.55%, 50.42% and 0.98% of the standard threshold, respectively. Half of community hypertensive patients did not control BP, and nearly a quarter have high risk of 10-years ASCVD risk estimation. The intensive threshold resulted in a one-third reduction in the control rate compared to the standard threshold. No matter which threshold was used, a single BP control status seemed not a suitable indicator for identification of high risk of 10-years ASCVD risk estimation. Nature Publishing Group UK 2021-09-24 /pmc/articles/PMC8463712/ /pubmed/34561523 http://dx.doi.org/10.1038/s41598-021-98745-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Liu, Shijun
Yuan, Hanyan
Jiang, Caixia
Xu, Jue
Qiu, Xin
Luo, Jun
The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title_full The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title_fullStr The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title_full_unstemmed The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title_short The blood pressure control and arteriosclerotic cardiovascular risk among Chinese community hypertensive patients
title_sort blood pressure control and arteriosclerotic cardiovascular risk among chinese community hypertensive patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463712/
https://www.ncbi.nlm.nih.gov/pubmed/34561523
http://dx.doi.org/10.1038/s41598-021-98745-8
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