Mitochondria-Rich Extracellular Vesicles Rescue Patient-Specific Cardiomyocytes From Doxorubicin Injury: Insights Into the SENECA Trial

BACKGROUND: Anthracycline-induced cardiomyopathy (AIC) is a significant source of morbidity and mortality in cancer survivors. The role of mesenchymal stem cells (MSCs) in treating AIC was evaluated in the SENECA trial, a Phase 1 National Heart, Lung, and Blood Institute–sponsored study, but the mec...

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Detalles Bibliográficos
Autores principales: O’Brien, Connor G., Ozen, Mehmet Ozgun, Ikeda, Gentaro, Vaskova, Evgeniya, Jung, Ji Hye, Bayardo, Nathan, Santoso, Michelle Rai, Shi, Liye, Wahlquist, Christine, Jiang, Zewen, Jung, Yunshin, Zeng, Yitian, Egan, Elizabeth, Sinclair, Robert, Gee, Adrian, Witteles, Ronald, Mercola, Mark, Svensson, Katrin J., Demirci, Utkan, Yang, Phillip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463733/
https://www.ncbi.nlm.nih.gov/pubmed/34604804
http://dx.doi.org/10.1016/j.jaccao.2021.05.006

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