Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI

A 63-year-old lady with a background of ischemic heart disease was referred for (18)F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnos...

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Detalles Bibliográficos
Autores principales: Yuheng Jiang, James, Wong, Veronica Chi Ken, Yun, James, Pathan, Faraz, Mansberg, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463740/
https://www.ncbi.nlm.nih.gov/pubmed/34603568
http://dx.doi.org/10.1016/j.radcr.2021.08.055
Descripción
Sumario:A 63-year-old lady with a background of ischemic heart disease was referred for (18)F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnosis of sarcoidosis was pathologically confirmed with bone biopsy. Following treatment, repeat PET/CT revealed significant regression of FDG avid lesions, however prominent uptake in the lateral ventricular wall was suspicious for active cardiac sarcoidosis, particularly given recurrent chest pain. This was confirmed on cardiac MRI and correlation with PET enabled discrimination between ischemic and non-ischemic fibrosis.

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