Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI

A 63-year-old lady with a background of ischemic heart disease was referred for (18)F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnos...

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Detalles Bibliográficos
Autores principales: Yuheng Jiang, James, Wong, Veronica Chi Ken, Yun, James, Pathan, Faraz, Mansberg, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463740/
https://www.ncbi.nlm.nih.gov/pubmed/34603568
http://dx.doi.org/10.1016/j.radcr.2021.08.055
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author Yuheng Jiang, James
Wong, Veronica Chi Ken
Yun, James
Pathan, Faraz
Mansberg, Robert
author_facet Yuheng Jiang, James
Wong, Veronica Chi Ken
Yun, James
Pathan, Faraz
Mansberg, Robert
author_sort Yuheng Jiang, James
collection PubMed
description A 63-year-old lady with a background of ischemic heart disease was referred for (18)F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnosis of sarcoidosis was pathologically confirmed with bone biopsy. Following treatment, repeat PET/CT revealed significant regression of FDG avid lesions, however prominent uptake in the lateral ventricular wall was suspicious for active cardiac sarcoidosis, particularly given recurrent chest pain. This was confirmed on cardiac MRI and correlation with PET enabled discrimination between ischemic and non-ischemic fibrosis.
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spelling pubmed-84637402021-10-01 Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI Yuheng Jiang, James Wong, Veronica Chi Ken Yun, James Pathan, Faraz Mansberg, Robert Radiol Case Rep Case Report A 63-year-old lady with a background of ischemic heart disease was referred for (18)F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnosis of sarcoidosis was pathologically confirmed with bone biopsy. Following treatment, repeat PET/CT revealed significant regression of FDG avid lesions, however prominent uptake in the lateral ventricular wall was suspicious for active cardiac sarcoidosis, particularly given recurrent chest pain. This was confirmed on cardiac MRI and correlation with PET enabled discrimination between ischemic and non-ischemic fibrosis. Elsevier 2021-09-20 /pmc/articles/PMC8463740/ /pubmed/34603568 http://dx.doi.org/10.1016/j.radcr.2021.08.055 Text en Crown Copyright © 2021 Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yuheng Jiang, James
Wong, Veronica Chi Ken
Yun, James
Pathan, Faraz
Mansberg, Robert
Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title_full Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title_fullStr Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title_full_unstemmed Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title_short Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)F-FDG PET/CT and cardiac MRI
title_sort disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on (18)f-fdg pet/ct and cardiac mri
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463740/
https://www.ncbi.nlm.nih.gov/pubmed/34603568
http://dx.doi.org/10.1016/j.radcr.2021.08.055
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