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Primary Testis Leiomyosarcoma: A Case Report

Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without...

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Autores principales: Nazar, Elham, Shabanzadeh, Zohre, Ahmadi, Amir, Rostami, Niloofar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463765/
https://www.ncbi.nlm.nih.gov/pubmed/34567199
http://dx.doi.org/10.30699/ijp.2021.524644.2586
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author Nazar, Elham
Shabanzadeh, Zohre
Ahmadi, Amir
Rostami, Niloofar
author_facet Nazar, Elham
Shabanzadeh, Zohre
Ahmadi, Amir
Rostami, Niloofar
author_sort Nazar, Elham
collection PubMed
description Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn’t receive any adjuvant therapy. There wasn’t any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors.
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spelling pubmed-84637652021-09-25 Primary Testis Leiomyosarcoma: A Case Report Nazar, Elham Shabanzadeh, Zohre Ahmadi, Amir Rostami, Niloofar Iran J Pathol Case Report Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn’t receive any adjuvant therapy. There wasn’t any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors. Iranian Society of Pathology 2021 2021-07-06 /pmc/articles/PMC8463765/ /pubmed/34567199 http://dx.doi.org/10.30699/ijp.2021.524644.2586 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution- 4.0 International License, (https://creativecommons.org/licenses/by/4.0/) which permits Share, copy and redistribution of the material in any medium or format or adapt, remix, transform, and build upon the material for any purpose, even commercially
spellingShingle Case Report
Nazar, Elham
Shabanzadeh, Zohre
Ahmadi, Amir
Rostami, Niloofar
Primary Testis Leiomyosarcoma: A Case Report
title Primary Testis Leiomyosarcoma: A Case Report
title_full Primary Testis Leiomyosarcoma: A Case Report
title_fullStr Primary Testis Leiomyosarcoma: A Case Report
title_full_unstemmed Primary Testis Leiomyosarcoma: A Case Report
title_short Primary Testis Leiomyosarcoma: A Case Report
title_sort primary testis leiomyosarcoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463765/
https://www.ncbi.nlm.nih.gov/pubmed/34567199
http://dx.doi.org/10.30699/ijp.2021.524644.2586
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