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Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies

Brain-imaging research on intentional decision-making often employs a “free-choice” paradigm, in which participants choose among options with identical values or outcomes. Although the medial prefrontal cortex has commonly been associated with choices, there is no consensus on the wider network that...

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Autores principales: Si, Ruoguang, Rowe, James B, Zhang, Jiaxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463837/
https://www.ncbi.nlm.nih.gov/pubmed/34390878
http://dx.doi.org/10.1016/j.neuroimage.2021.118468
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author Si, Ruoguang
Rowe, James B
Zhang, Jiaxiang
author_facet Si, Ruoguang
Rowe, James B
Zhang, Jiaxiang
author_sort Si, Ruoguang
collection PubMed
description Brain-imaging research on intentional decision-making often employs a “free-choice” paradigm, in which participants choose among options with identical values or outcomes. Although the medial prefrontal cortex has commonly been associated with choices, there is no consensus on the wider network that underlies diverse intentional decisions and behaviours. Our systematic literature search identified 35 fMRI/PET experiments using various free-choice paradigms, with appropriate control conditions using external instructions. An Activation Likelihood Estimate (ALE) meta-analysis showed that, compared with external instructions, intentional decisions consistently activate the medial and dorsolateral prefrontal cortex, the left insula and the inferior parietal lobule. We then categorized the studies into four different types according to their experimental designs: reactive motor intention, perceptual intention, inhibitory intention, and cognitive intention. We conducted conjunction and contrast meta-analyses to identify consistent and selective spatial convergence of brain activation within each specific category of intentional decision. Finally, we used meta-analytic decoding to probe cognitive processes underlying free choices. Our findings suggest that the neurocognitive process underlying intentional decision incorporates anatomically separated components subserving distinct cognitive and computational roles.
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spelling pubmed-84638372021-11-15 Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies Si, Ruoguang Rowe, James B Zhang, Jiaxiang Neuroimage Article Brain-imaging research on intentional decision-making often employs a “free-choice” paradigm, in which participants choose among options with identical values or outcomes. Although the medial prefrontal cortex has commonly been associated with choices, there is no consensus on the wider network that underlies diverse intentional decisions and behaviours. Our systematic literature search identified 35 fMRI/PET experiments using various free-choice paradigms, with appropriate control conditions using external instructions. An Activation Likelihood Estimate (ALE) meta-analysis showed that, compared with external instructions, intentional decisions consistently activate the medial and dorsolateral prefrontal cortex, the left insula and the inferior parietal lobule. We then categorized the studies into four different types according to their experimental designs: reactive motor intention, perceptual intention, inhibitory intention, and cognitive intention. We conducted conjunction and contrast meta-analyses to identify consistent and selective spatial convergence of brain activation within each specific category of intentional decision. Finally, we used meta-analytic decoding to probe cognitive processes underlying free choices. Our findings suggest that the neurocognitive process underlying intentional decision incorporates anatomically separated components subserving distinct cognitive and computational roles. Academic Press 2021-11-15 /pmc/articles/PMC8463837/ /pubmed/34390878 http://dx.doi.org/10.1016/j.neuroimage.2021.118468 Text en © 2021 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Si, Ruoguang
Rowe, James B
Zhang, Jiaxiang
Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title_full Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title_fullStr Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title_full_unstemmed Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title_short Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies
title_sort functional localization and categorization of intentional decisions in humans: a meta-analysis of brain imaging studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463837/
https://www.ncbi.nlm.nih.gov/pubmed/34390878
http://dx.doi.org/10.1016/j.neuroimage.2021.118468
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