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Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase
BACKGROUND & AIMS: Patients with simple steatosis (SS) and nonalcoholic steatohepatitis can develop progressive liver fibrosis, which is associated with liver-related mortality. The mechanisms contributing to liver fibrosis development in SS, however, are poorly understood. SS is characterized b...
Autores principales: | Salloum, Shadi, Jeyarajan, Andre J., Kruger, Annie J., Holmes, Jacinta A., Shao, Tuo, Sojoodi, Mozhdeh, Kim, Myung-Ho, Zhuo, Zhu, Shroff, Stuti G., Kassa, Andrew, Corey, Kathleen E., Khan, Sanjoy K., Lin, Wenyu, Alatrakchi, Nadia, Schaefer, Esperance A.K., Chung, Raymond T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463869/ https://www.ncbi.nlm.nih.gov/pubmed/34118488 http://dx.doi.org/10.1016/j.jcmgh.2021.06.003 |
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