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The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces

Molecular chaperones are key components of the cellular proteostasis network whose role includes the suppression of the formation and proliferation of pathogenic aggregates associated with neurodegenerative diseases. The molecular principles that allow chaperones to recognize misfolded and aggregate...

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Detalles Bibliográficos
Autores principales:	Scheidt, Tom, Carozza, Jacqueline A., Kolbe, Carl C., Aprile, Francesco A., Tkachenko, Olga, Bellaiche, Mathias M. J., Meisl, Georg, Peter, Quentin A. E., Herling, Therese W., Ness, Samuel, Castellana-Cruz, Marta, Benesch, Justin L. P., Vendruscolo, Michele, Dobson, Christopher M., Arosio, Paolo, Knowles, Tuomas P. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463877/ https://www.ncbi.nlm.nih.gov/pubmed/34518228 http://dx.doi.org/10.1073/pnas.2108790118

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