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Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes axon growth

The rapid formation of a glial/fibrotic scar is one of the main factors hampering axon growth after spinal cord injury. The bidirectional EphB2/ephrin-B2 signaling of the fibroblast-astrocyte contact-dependent interaction is a trigger for glial/fibrotic scar formation. In the present study, a new in...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Zhu, Zhen-Yu, Fan, Zhi-Wei, Chen, Ying, Yang, Ri-Yun, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463997/
https://www.ncbi.nlm.nih.gov/pubmed/34269211
http://dx.doi.org/10.4103/1673-5374.317988