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Insights into the dual functions of AcrIF14 during the inhibition of type I-F CRISPR–Cas surveillance complex

CRISPR–Cas systems are bacterial adaptive immune systems, and phages counteract these systems using many approaches such as producing anti-CRISPR (Acr) proteins. Here, we report the structures of both AcrIF14 and its complex with the crRNA-guided surveillance (Csy) complex. Our study demonstrates th...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Zhang, Laixing, Xiu, Yu, Gao, Teng, Huang, Ling, Xie, Yongchao, Yang, Lingguang, Wang, Wenhe, Wang, Peiyi, Zhang, Yi, Yang, Maojun, Feng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464039/
https://www.ncbi.nlm.nih.gov/pubmed/34432044
http://dx.doi.org/10.1093/nar/gkab738