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NgAgo possesses guided DNA nicking activity

Prokaryotic Argonautes (pAgos) have been proposed as more flexible tools for gene-editing as they do not require sequence motifs adjacent to their targets for function, unlike popular CRISPR/Cas systems. One promising pAgo candidate, from the halophilic archaeon Natronobacterium gregoryi (NgAgo), ha...

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Detalles Bibliográficos
Autores principales:	Lee, Kok Zhi, Mechikoff, Michael A, Kikla, Archana, Liu, Arren, Pandolfi, Paula, Fitzgerald, Kevin, Gimble, Frederick S, Solomon, Kevin V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464042/ https://www.ncbi.nlm.nih.gov/pubmed/34478558 http://dx.doi.org/10.1093/nar/gkab757

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