The RNA binding protein Quaking represses splicing of the Fibronectin EDA exon and downregulates the interferon response

Quaking (QKI) controls RNA metabolism in many biological processes including innate immunity, where its roles remain incompletely understood. To illuminate these roles, we performed genome scale transcriptome profiling in QKI knockout cells with or without poly(I:C) transfection, a double-stranded R...

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Detalles Bibliográficos
Autores principales: Liao, Kuo-Chieh, Chuo, Vanessa, Fagg, W Samuel, Modahl, Cassandra M, Widen, Steven, Garcia-Blanco, Mariano A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464043/
https://www.ncbi.nlm.nih.gov/pubmed/34428287
http://dx.doi.org/10.1093/nar/gkab732

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