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Twice exploration of tRNA +1 frameshifting in an elongation cycle of protein synthesis
Inducing tRNA +1 frameshifting to read a quadruplet codon has the potential to incorporate a non-natural amino acid into the polypeptide chain. While this strategy is being considered for genome expansion in biotechnology and bioengineering endeavors, a major limitation is a lack of understanding of...
Autores principales: | Gamper, Howard, Mao, Yujia, Masuda, Isao, McGuigan, Henri, Blaha, Gregor, Wang, Yuhong, Xu, Shoujun, Hou, Ya-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464047/ https://www.ncbi.nlm.nih.gov/pubmed/34417618 http://dx.doi.org/10.1093/nar/gkab734 |
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