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X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications

AaRSs (aminoacyl-tRNA synthetases) group into two ten-member classes throughout evolution, with unique active site architectures defining each class. Most are monomers or homodimers but, for no apparent reason, many bacterial GlyRSs are heterotetramers consisting of two catalytic α-subunits and two...

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Detalles Bibliográficos
Autores principales:	Ju, Yingchen, Han, Lu, Chen, Bingyi, Luo, Zhiteng, Gu, Qiong, Xu, Jun, Yang, Xiang-Lei, Schimmel, Paul, Zhou, Huihao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464048/ https://www.ncbi.nlm.nih.gov/pubmed/34390350 http://dx.doi.org/10.1093/nar/gkab707

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