Cargando…

The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout

The iron-dependent regulator IdeR is the main transcriptional regulator controlling iron homeostasis genes in Actinobacteria, including species from the Corynebacterium, Mycobacterium and Streptomyces genera, as well as the erythromycin-producing bacterium Saccharopolyspora erythraea. Despite being...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marcos-Torres, Francisco Javier, Maurer, Dirk, Juniar, Linda, Griese, Julia J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464063/ https://www.ncbi.nlm.nih.gov/pubmed/34417623 http://dx.doi.org/10.1093/nar/gkab711

Ejemplares similares

The molecular mechanisms of the bacterial iron sensor IdeR
por: Marcos-Torres, Francisco Javier, et al.
Publicado: (2023)

Design of peptides interfering with iron-dependent regulator (IdeR) and evaluation of Mycobacterium tuberculosis growth inhibition
por: Salimizand, Himen, et al.
Publicado: (2017)

Mechanism of Iron-Dependent Repressor (IdeR) Activation and DNA Binding: A Molecular Dynamics and Protein Structure Network Study
por: Ghosh, Soma, et al.
Publicado: (2015)

Zinc excess impairs Mycobacterium bovis growth through triggering a Zur-IdeR-iron homeostasis signal pathway
por: Li, Xiaohui, et al.
Publicado: (2023)

Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti-Mycobacterium ulcerans Natural Product-Derived Compounds
por: Kwofie, Samuel K., et al.
Publicado: (2019)

DNA sequence-specific recognition by a transcriptional regulator requires indirect readout of A-tracts
por: Mendieta, Jesús, et al.
Publicado: (2007)

Virtual Screening, pharmacophore development and structure based similarity search to identify inhibitors against IdeR, a transcription factor of Mycobacterium tuberculosis
por: Rohilla, Akshay, et al.
Publicado: (2017)

Dissecting direct and indirect readout of cAMP receptor protein DNA binding using an inosine and 2,6-diaminopurine in vitro selection system
por: Lindemose, Søren, et al.
Publicado: (2008)

ArrayIDer: automated structural re-annotation pipeline for DNA microarrays
por: van den Berg, Bart HJ, et al.
Publicado: (2009)

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex
por: Stratmann, Sarah A, et al.
Publicado: (2015)

The intrinsically disordered distal face of nucleoplasmin recognizes distinct oligomerization states of histones
por: Ramos, Isbaal, et al.
Publicado: (2014)

sppIDer: A Species Identification Tool to Investigate Hybrid Genomes with High-Throughput Sequencing
por: Langdon, Quinn K, et al.
Publicado: (2018)

Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins
por: Griese, Julia J., et al.
Publicado: (2010)

ReadOut: structure-based calculation of direct and indirect readout energies and specificities for protein–DNA recognition
por: Ahmad, Shandar, et al.
Publicado: (2006)

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically
por: Kaus-Drobek, Magdalena, et al.
Publicado: (2007)

Structural basis for the Smad5 MH1 domain to recognize different DNA sequences
por: Chai, Nan, et al.
Publicado: (2015)

LipidA-IDER to Explore the Global Lipid A Repertoire of Drug-Resistant Gram-Negative Bacteria
por: Guan, Xue Li, et al.
Publicado: (2023)

The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA
por: Lancelot, Nathalie, et al.
Publicado: (2007)

UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions
por: Meulenbroek, Elisabeth M., et al.
Publicado: (2013)

Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA
por: Jayachandran, Uma, et al.
Publicado: (2016)

Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region
por: Wen, Yurong, et al.
Publicado: (2017)

The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin
por: Tian, Wei, et al.
Publicado: (2019)

Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation
por: Araúzo-Bravo, Marcos J., et al.
Publicado: (2008)

Crystallographic analysis and phasing of iron-assimilating protein 1 (FEA1) from Chlamydomonas reinhardtii
por: Juniar, Linda, et al.
Publicado: (2021)

The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
por: Tanzawa, Takehito, et al.
Publicado: (2018)

The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA
por: Cuypers, Maxime G, et al.
Publicado: (2018)

Crystal twinning of human MD-2 recognizing endotoxin cores of lipopolysaccharide
por: Ohto, Umeharu, et al.
Publicado: (2008)

Two coexisting pseudo-mirror heteromolecular telomeric G-quadruplexes in opposite loop progressions differentially recognized by a low equivalent of Thioflavin T
por: Fu, Wenqiang, et al.
Publicado: (2021)

Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry
por: Zhao, Gong, et al.
Publicado: (2014)

IdeS: A Bacterial Proteolytic Enzyme with Therapeutic Potential
por: Johansson, Björn P., et al.
Publicado: (2008)

The structure of the bacterial iron–catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism
por: Grinter, Rhys, et al.
Publicado: (2019)

Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals
por: Fung, Ho Yee Joyce, et al.
Publicado: (2017)

Peptide-binding dependent conformational changes regulate the transcriptional activity of the quorum-sensor NprR
por: Zouhir, Samira, et al.
Publicado: (2013)

Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism
por: Yang, Qianfan, et al.
Publicado: (2010)

Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR
por: Freda, Ida, et al.
Publicado: (2023)

A Rare Case of Microgranular Acute Promyelocytic Leukemia Associated with ider(17)(q10)t(15;17) in an Old-age Patient
por: Kim, Min Jin, et al.
Publicado: (2011)

Tertiary structure of bacterial selenocysteine tRNA
por: Itoh, Yuzuru, et al.
Publicado: (2013)

Structure of the complete bacterial SRP Alu domain
por: Kempf, Georg, et al.
Publicado: (2014)

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence
por: Wen, Yurong, et al.
Publicado: (2014)

Readout Circuits for Capacitive Sensors
por: Yoo, Yongsang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g55lu8mibej3n83s7chrbrtp5g