The Polycomb protein RING1B enables estrogen-mediated gene expression by promoting enhancer–promoter interaction and R-loop formation

Polycomb complexes have traditionally been prescribed roles as transcriptional repressors, though increasing evidence demonstrate they can also activate gene expression. However, the mechanisms underlying positive gene regulation mediated by Polycomb proteins are poorly understood. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Zhang, Yusheng, Liu, Tong, Yuan, Fenghua, Garcia-Martinez, Liliana, Lee, Kyutae D, Stransky, Stephanie, Sidoli, Simone, Verdun, Ramiro E, Zhang, Yanbin, Wang, Zheng, Morey, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464076/
https://www.ncbi.nlm.nih.gov/pubmed/34428304
http://dx.doi.org/10.1093/nar/gkab723

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