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TGF-β-Induced TMEPAI Promotes Epithelial–Mesenchymal Transition in Doxorubicin-Treated Triple-Negative Breast Cancer Cells via SMAD3 and PI3K/AKT Pathway Alteration

INTRODUCTION: Epithelial–mesenchymal transition (EMT) and overexpression of drug efflux transporters have been reported to cause doxorubicin resistance. Our previous study indicated that TMEPAI (transmembrane prostate androgen-induced protein) attenuated doxorubicin sensitivity in triple-negative br...

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Detalles Bibliográficos
Autores principales: Wardhani, Bantari W K, Louisa, Melva, Watanabe, Yukihide, Setiabudy, Rianto, Kato, Mitsuyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464328/
https://www.ncbi.nlm.nih.gov/pubmed/34584450
http://dx.doi.org/10.2147/BCTT.S325429