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A Review on Strongyloidiasis in Pregnant Women
Strongyloidiasis is a parasitic infection distributed worldwide, with an estimated 614 million people infected. Strongyloidiasis usually presents asymptomatically or with aspecific and mild clinical symptoms, mainly cutaneous, respiratory, or gastrointestinal. Disseminated disease and hyperinfection...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464358/ https://www.ncbi.nlm.nih.gov/pubmed/34584485 http://dx.doi.org/10.2147/RRTM.S282268 |
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author | Wikman-Jorgensen, Philip Requena-Méndez, Ana Llenas-García, Jara |
author_facet | Wikman-Jorgensen, Philip Requena-Méndez, Ana Llenas-García, Jara |
author_sort | Wikman-Jorgensen, Philip |
collection | PubMed |
description | Strongyloidiasis is a parasitic infection distributed worldwide, with an estimated 614 million people infected. Strongyloidiasis usually presents asymptomatically or with aspecific and mild clinical symptoms, mainly cutaneous, respiratory, or gastrointestinal. Disseminated disease and hyperinfection syndrome are the most serious complications, have a high mortality rate, usually occur in immunosuppressed patients, and are particularly associated with the use of corticosteroids. Strongyloidiasis is the most neglected of the neglected diseases, and its occurrence in pregnancy has been neglected and understudied. In this review, we focus on the effects of strongyloidiasis during pregnancy and highlight the knowledge shortage and the need for more research on the subject. There are few studies addressing strongyloidiasis prevalence during pregnancy and hyperinfection incidence during pregnancy is practically unknown, with only isolated case reports published. Although data are scarce, the infection has been associated with developmental disabilities and anemia during pregnancy, while hyperinfection may cause both maternal and neonatal death. Data on the best screening and diagnostic strategies during pregnancy are lacking. There is insufficient evidence on ivermectin safety in pregnancy, complicating treatment recommendations. |
format | Online Article Text |
id | pubmed-8464358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-84643582021-09-27 A Review on Strongyloidiasis in Pregnant Women Wikman-Jorgensen, Philip Requena-Méndez, Ana Llenas-García, Jara Res Rep Trop Med Review Strongyloidiasis is a parasitic infection distributed worldwide, with an estimated 614 million people infected. Strongyloidiasis usually presents asymptomatically or with aspecific and mild clinical symptoms, mainly cutaneous, respiratory, or gastrointestinal. Disseminated disease and hyperinfection syndrome are the most serious complications, have a high mortality rate, usually occur in immunosuppressed patients, and are particularly associated with the use of corticosteroids. Strongyloidiasis is the most neglected of the neglected diseases, and its occurrence in pregnancy has been neglected and understudied. In this review, we focus on the effects of strongyloidiasis during pregnancy and highlight the knowledge shortage and the need for more research on the subject. There are few studies addressing strongyloidiasis prevalence during pregnancy and hyperinfection incidence during pregnancy is practically unknown, with only isolated case reports published. Although data are scarce, the infection has been associated with developmental disabilities and anemia during pregnancy, while hyperinfection may cause both maternal and neonatal death. Data on the best screening and diagnostic strategies during pregnancy are lacking. There is insufficient evidence on ivermectin safety in pregnancy, complicating treatment recommendations. Dove 2021-09-21 /pmc/articles/PMC8464358/ /pubmed/34584485 http://dx.doi.org/10.2147/RRTM.S282268 Text en © 2021 Wikman-Jorgensen et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Wikman-Jorgensen, Philip Requena-Méndez, Ana Llenas-García, Jara A Review on Strongyloidiasis in Pregnant Women |
title | A Review on Strongyloidiasis in Pregnant Women |
title_full | A Review on Strongyloidiasis in Pregnant Women |
title_fullStr | A Review on Strongyloidiasis in Pregnant Women |
title_full_unstemmed | A Review on Strongyloidiasis in Pregnant Women |
title_short | A Review on Strongyloidiasis in Pregnant Women |
title_sort | review on strongyloidiasis in pregnant women |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464358/ https://www.ncbi.nlm.nih.gov/pubmed/34584485 http://dx.doi.org/10.2147/RRTM.S282268 |
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