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Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis
RAC1B is a tumour-related alternative splice isoform of the small GTPase RAC1, found overexpressed in a large number of tumour types. Building evidence suggests it promotes tumour progression but compelling in vivo evidence, demonstrating a role in driving tumour invasion, is currently lacking. In t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464603/ https://www.ncbi.nlm.nih.gov/pubmed/34564693 http://dx.doi.org/10.1038/s41419-021-04177-7 |