Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload

Progressive cardiac fibrosis accelerates the development of heart failure. Here, we aimed to explore serum Wnt5a and Wnt11 levels in hypertension patients, the roles of Wnt5a and Wnt11 in cardiac fibrosis and potential mechanisms under pressure overload. The pressure overload mouse model was built b...

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Detalles Bibliográficos
Autores principales: Zou, Yan, Pan, Le, Shen, Yi, Wang, Xiang, Huang, Chenxing, Wang, Hao, Jin, Xuejuan, Yin, Chao, Wang, Ying, Jia, Jianguo, Qian, Juying, Zou, Yunzeng, Gong, Hui, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464604/
https://www.ncbi.nlm.nih.gov/pubmed/34564708
http://dx.doi.org/10.1038/s41419-021-04152-2

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