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Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer

The poor prognosis of pancreatic cancer is primarily due to the development of resistance to therapies, including gemcitabine. The long noncoding RNA PVT1 (lncRNA PVT1) has been shown to interact with enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), promoting gemcitabine resistance...

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Detalles Bibliográficos
Autores principales:	Sun, Yan, Ren, Dianyun, Zhou, Yingke, Shen, Jian, Wu, Heshui, Jin, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464605/ https://www.ncbi.nlm.nih.gov/pubmed/34564701 http://dx.doi.org/10.1038/s41419-021-04118-4

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