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Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury

The role of nintedanib, a multiple tyrosine kinase inhibitor, in the treatment of sepsis-induced acute lung injury (ALI) remains unclear. Lipopolysaccharide (LPS), also known as endotoxin, has been used to induce ALI. The goal of this study was to assess the effect of nintedanib in attenuating the h...

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Detalles Bibliográficos
Autores principales: Su, Vincent Yi-Fong, Chen, Wei-Chih, Yu, Wen-Kuang, Wu, Huai-Hsuan, Chen, Hao, Yang, Kuang-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464681/
https://www.ncbi.nlm.nih.gov/pubmed/34576061
http://dx.doi.org/10.3390/ijms22189898

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