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Enhanced Thermostability of D-Psicose 3-Epimerase from Clostridium bolteae through Rational Design and Engineering of New Disulfide Bridges
D-psicose 3-epimerase (DPEase) catalyzes the isomerization of D-fructose to D-psicose (aka D-allulose, a low-calorie sweetener), but its industrial application has been restricted by the poor thermostability of the naturally available enzymes. Computational rational design of disulfide bridges was u...
Autores principales: | Zhao, Jingyi, Chen, Jing, Wang, Huiyi, Guo, Yan, Li, Kai, Liu, Jidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464696/ https://www.ncbi.nlm.nih.gov/pubmed/34576170 http://dx.doi.org/10.3390/ijms221810007 |
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