Cargando…

Quantitative Proteomics and Phosphoproteomics Reveal TNF-α-Mediated Protein Functions in Hepatocytes

Increased secretion of proinflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), is often associated with adipose tissue dysregulation, which often accompanies obesity. High levels of TNFα have been linked to the development of insulin resistance in several tissues and organs, including...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohallem, Rodrigo, Aryal, Uma K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464716/ https://www.ncbi.nlm.nih.gov/pubmed/34576943 http://dx.doi.org/10.3390/molecules26185472

Ejemplares similares

Regulators of TNFα mediated insulin resistance elucidated by quantitative proteomics
por: Mohallem, Rodrigo, et al.
Publicado: (2020)

Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation
por: Coleman, Rachel A., et al.
Publicado: (2021)

Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics
por: Doubleday, Peter F., et al.
Publicado: (2014)

Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate
por: Krishnan, Ramesh K., et al.
Publicado: (2015)

Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development
por: Zheng, Ya, et al.
Publicado: (2023)

Shotgun proteomics of homogenate milk reveals dynamic changes in protein abundances between colostrum, transitional, and mature milk of swine
por: Bradshaw, Christina V, et al.
Publicado: (2021)

Multi-Omics Approach Reveals Dysregulation of Protein Phosphorylation Correlated with Lipid Metabolism in Mouse Non-Alcoholic Fatty Liver
por: Kim, Sora Q., et al.
Publicado: (2022)

Temporal Quantitative Proteomics Reveals Proteomic and Phosphoproteomic Alterations Associated with Adaptive Response to Hypoxia in Melanoma Cells
por: Datta, Keshava K., et al.
Publicado: (2021)

Proteomic analysis reveals that aging rabbit vocal folds are more vulnerable to changes caused by systemic dehydration
por: do Nascimento, Naila C., et al.
Publicado: (2022)

Proteomic Analysis of 3T3-L1 Adipocytes Treated with Insulin and TNF-α
por: Chan, Hayley, et al.
Publicado: (2019)

Proteome and Phosphoproteome Analysis in TNF Long Term-Exposed Primary Human Monocytes
por: Welz, Bastian, et al.
Publicado: (2019)

Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1
por: Bass, Thomas E., et al.
Publicado: (2019)

Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration
por: Sarhan, Adil R., et al.
Publicado: (2017)

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer’s disease
por: Ping, Lingyan, et al.
Publicado: (2020)

Quantitative proteome and phosphoproteome datasets of DNA replication and mitosis in Saccharomyces cerevisiae
por: Rossio, Valentina, et al.
Publicado: (2022)

Quantitative analyses of the global proteome and phosphoproteome reveal the different impacts of propofol and dexmedetomidine on HT22 cells
por: Zhang, Honggang, et al.
Publicado: (2017)

Salinity-Induced Palmella Formation Mechanism in Halotolerant Algae Dunaliella salina Revealed by Quantitative Proteomics and Phosphoproteomics
por: Wei, Sijia, et al.
Publicado: (2017)

Modeling the TNFα-Induced Apoptosis Pathway in Hepatocytes
por: Schlatter, Rebekka, et al.
Publicado: (2011)

Quantitative phosphoproteomic analysis reveals involvement of PD-1 in multiple T cell functions
por: Tocheva, Anna S., et al.
Publicado: (2021)

Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics
por: Gao, Li, et al.
Publicado: (2023)

Systems-wide Analysis of a Phosphatase Knock-down by Quantitative Proteomics and Phosphoproteomics
por: Hilger, Maximiliane, et al.
Publicado: (2009)

Isotopically Dimethyl Labeling-Based Quantitative Proteomic Analysis of Phosphoproteomes of Soybean Cultivars
por: Moradi, Atieh, et al.
Publicado: (2021)

Quantitative proteomic analysis of enhanced cellular effects of electrochemotherapy with Cisplatin in triple-negative breast cancer cells
por: Mittal, Lakshya, et al.
Publicado: (2019)

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
por: Su, Zhiduan, et al.
Publicado: (2019)

Quantitative Phosphoproteomics of Cytotoxic T Cells to Reveal Protein Kinase D 2 Regulated Networks
por: Navarro, María N., et al.
Publicado: (2014)

Quantitative proteome and phosphoproteome analyses highlight the adherent population during Trypanosoma cruzi metacyclogenesis
por: Amorim, Juliana C., et al.
Publicado: (2017)

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics
por: Jensen, Pia, et al.
Publicado: (2017)

Proteomic and Phosphoproteomic Profiling Reveals the Oncogenic Role of Protein Kinase D Family Kinases in Cholangiocarcinoma
por: Lu, Yun, et al.
Publicado: (2022)

Quantitative proteomic and phosphoproteomic analyses of the hippocampus reveal the involvement of NMDAR1 signaling in repetitive mild traumatic brain injury
por: Tian, Zhicheng, et al.
Publicado: (2023)

Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast
por: Li, Jiaming, et al.
Publicado: (2019)

Author Correction: Quantitative proteomic analysis of enhanced cellular effects of electrochemotherapy with Cisplatin in triple-negative breast cancer cells
por: Mittal, Lakshya, et al.
Publicado: (2019)

Urinary proteomic and non-prefractionation quantitative phosphoproteomic analysis during pregnancy and non-pregnancy
por: Zheng, Jianhua, et al.
Publicado: (2013)

Excessive Inorganic Phosphate Burden Perturbed Intracellular Signaling: Quantitative Proteomics and Phosphoproteomics Analyses
por: Hetz, Rebecca, et al.
Publicado: (2022)

Global Effects of Kinase Inhibitors on Signaling Networks Revealed by Quantitative Phosphoproteomics
por: Pan, Cuiping, et al.
Publicado: (2009)

Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome
por: Liu, Yixian, et al.
Publicado: (2021)

The regulatory role of microRNA-1187 in TNF-α-mediated hepatocyte apoptosis in acute liver failure
por: YU, DONG SHAN, et al.
Publicado: (2012)

Quantitative Dynamics of Phosphoproteome: The Devil Is in the Details
por: Salek, Mogjiborahman, et al.
Publicado: (2012)

Extracellular Matrix Proteome and Phosphoproteome of Potato Reveals Functionally Distinct and Diverse Canonical and Non-Canonical Proteoforms
por: Elagamey, Eman, et al.
Publicado: (2016)

Quantitative Proteomic and Phosphoproteomic Profiling of Lung Tissues from Pulmonary Arterial Hypertension Rat Model
por: Luo, Ang, et al.
Publicado: (2023)

Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease
por: Hadisurya, Marco, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m8a9iad7fpijeu9lh5nu511l95