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Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation

Liver fibrosis is characterized by the accumulation of extracellular matrix (ECM) resulting in the formation of fibrous scars. In the clinic, liver biopsies are the standard diagnostic method despite the potential for clinical complications. miRNAs are single-stranded, non-coding RNAs that can be de...

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Detalles Bibliográficos
Autores principales: Messner, Catherine Jane, Schmidt, Saskia, Özkul, Dilek, Gaiser, Carine, Terracciano, Luigi, Krähenbühl, Stephan, Suter-Dick, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464755/
https://www.ncbi.nlm.nih.gov/pubmed/34575957
http://dx.doi.org/10.3390/ijms22189799