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Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation
Liver fibrosis is characterized by the accumulation of extracellular matrix (ECM) resulting in the formation of fibrous scars. In the clinic, liver biopsies are the standard diagnostic method despite the potential for clinical complications. miRNAs are single-stranded, non-coding RNAs that can be de...
Autores principales: | Messner, Catherine Jane, Schmidt, Saskia, Özkul, Dilek, Gaiser, Carine, Terracciano, Luigi, Krähenbühl, Stephan, Suter-Dick, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464755/ https://www.ncbi.nlm.nih.gov/pubmed/34575957 http://dx.doi.org/10.3390/ijms22189799 |
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