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Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions

Plants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negat...

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Autores principales: Olejnik, Przemysław, Mądrzak, Cezary Jerzy, Nuc, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464771/
https://www.ncbi.nlm.nih.gov/pubmed/34572603
http://dx.doi.org/10.3390/biom11091390
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author Olejnik, Przemysław
Mądrzak, Cezary Jerzy
Nuc, Katarzyna
author_facet Olejnik, Przemysław
Mądrzak, Cezary Jerzy
Nuc, Katarzyna
author_sort Olejnik, Przemysław
collection PubMed
description Plants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negatively affect the growth, development, yield and quality of plants, which is very important for crops. In contrast, the plant–microbe interaction could be growth-promoting. One of the proteins involved in plant response to stress conditions and plant–microbe interactions is cyclophilin. Cyclophilins (CyPs), together with FK506-binding proteins (FKBPs) and parvulins, belong to a big family of proteins with peptidyl-prolyl cis-trans isomerase activity (Enzyme Commission (EC) number 5.2.1.8). Genes coding for proteins with the CyP domain are widely expressed in all organisms examined, including bacteria, fungi, animals, and plants. Their different forms can be found in the cytoplasm, endoplasmic reticulum, nucleus, chloroplast, mitochondrion and in the phloem space. They are involved in numerous processes, such as protein folding, cellular signaling, mRNA processing, protein degradation and apoptosis. In the past few years, many new functions, and molecular mechanisms for cyclophilins have been discovered. In this review, we aim to summarize recent advances in cyclophilin research to improve our understanding of their biological functions in plant defense and symbiotic plant–microbe interactions.
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spelling pubmed-84647712021-09-27 Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions Olejnik, Przemysław Mądrzak, Cezary Jerzy Nuc, Katarzyna Biomolecules Review Plants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negatively affect the growth, development, yield and quality of plants, which is very important for crops. In contrast, the plant–microbe interaction could be growth-promoting. One of the proteins involved in plant response to stress conditions and plant–microbe interactions is cyclophilin. Cyclophilins (CyPs), together with FK506-binding proteins (FKBPs) and parvulins, belong to a big family of proteins with peptidyl-prolyl cis-trans isomerase activity (Enzyme Commission (EC) number 5.2.1.8). Genes coding for proteins with the CyP domain are widely expressed in all organisms examined, including bacteria, fungi, animals, and plants. Their different forms can be found in the cytoplasm, endoplasmic reticulum, nucleus, chloroplast, mitochondrion and in the phloem space. They are involved in numerous processes, such as protein folding, cellular signaling, mRNA processing, protein degradation and apoptosis. In the past few years, many new functions, and molecular mechanisms for cyclophilins have been discovered. In this review, we aim to summarize recent advances in cyclophilin research to improve our understanding of their biological functions in plant defense and symbiotic plant–microbe interactions. MDPI 2021-09-21 /pmc/articles/PMC8464771/ /pubmed/34572603 http://dx.doi.org/10.3390/biom11091390 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Olejnik, Przemysław
Mądrzak, Cezary Jerzy
Nuc, Katarzyna
Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title_full Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title_fullStr Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title_full_unstemmed Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title_short Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
title_sort cyclophilins and their functions in abiotic stress and plant–microbe interactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464771/
https://www.ncbi.nlm.nih.gov/pubmed/34572603
http://dx.doi.org/10.3390/biom11091390
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