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Targeting OLFML3 in Colorectal Cancer Suppresses Tumor Growth and Angiogenesis, and Increases the Efficacy of Anti-PD1 Based Immunotherapy
SIMPLE SUMMARY: Tumor vascularization promotes tumor growth and is intimately connected to immune system function. Despite efforts to use antiangiogenic therapies, their clinical effects are less pronounced than expected. Compensatory angiogenic responses and resistance to treatment are responsible...
Autores principales: | Stalin, Jimmy, Imhof, Beat A., Coquoz, Oriana, Jeitziner, Rachel, Hammel, Philippe, McKee, Thomas A., Jemelin, Stephane, Poittevin, Marine, Pocard, Marc, Matthes, Thomas, Kaci, Rachid, Delorenzi, Mauro, Rüegg, Curzio, Miljkovic-Licina, Marijana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464773/ https://www.ncbi.nlm.nih.gov/pubmed/34572851 http://dx.doi.org/10.3390/cancers13184625 |
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