Niclosamide and Pyrvinium Are Both Potential Therapeutics for Osteosarcoma, Inhibiting Wnt–Axin2–Snail Cascade

SIMPLE SUMMARY: Epithelial–mesenchymal transition (EMT) regulated by Wnt signaling is known as a key mechanism of cancer progression. Although evidence has suggested that the oncogenic Wnt signaling pathway and EMT program are important in the progression of osteosarcoma, there is no known therapeut...

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Detalles Bibliográficos
Autores principales: Yi, Young, Woo, Young Mi, Hwang, Kyu Ho, Kim, Hyun Sil, Lee, Sang Hyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464802/
https://www.ncbi.nlm.nih.gov/pubmed/34572856
http://dx.doi.org/10.3390/cancers13184630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464802/
https://www.ncbi.nlm.nih.gov/pubmed/34572856
http://dx.doi.org/10.3390/cancers13184630

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