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Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

Choline kinase inhibitors are an outstanding class of cytotoxic compounds useful for the treatment of different forms of cancer since aberrant choline metabolism is a feature of neoplastic cells. Here, we present the most in-depth structure-activity relationship studies of an interesting series of n...

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Detalles Bibliográficos
Autores principales: Schiaffino-Ortega, Santiago, Mariotto, Elena, Luque-Navarro, Pilar María, Kimatrai-Salvador, María, Rios-Marco, Pablo, Hurtado-Guerrero, Ramon, Marco, Carmen, Carrasco-Jimenez, María Paz, Viola, Giampietro, López-Cara, Luisa Carlota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464809/
https://www.ncbi.nlm.nih.gov/pubmed/34575436
http://dx.doi.org/10.3390/pharmaceutics13091360