Cargando…

Chemoreversal Agents from Taiwanofungus Genus and Their More Potent Methyl Derivatives Targeting Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation

Multidrug resistance (MDR), for which the mechanisms are not yet fully clear, is one of the major obstacles to cancer treatment. In recent years, signal transducer and activator of transcription 3 (STAT3) were found to be one of the important MDR mechanism pathways. Based on the previous research, z...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Ko-Hua, Hung, Chin-Chuan, Wu, Tian-Shung, Chen, Chin-Fu, Wu, I-Ting, Kuo, Ping-Chung, Lam, Sio-Hong, Hung, Hsin-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464893/ https://www.ncbi.nlm.nih.gov/pubmed/34577615 http://dx.doi.org/10.3390/ph14090916

Ejemplares similares

Constituents and Anti-Multidrug Resistance Activity of Taiwanofungus camphoratus on Human Cervical Cancer Cells
por: Hung, Hsin-Yi, et al.
Publicado: (2019)

Zhankuic Acids A, B and C from Taiwanofungus camphoratus Act as Cytotoxicity Enhancers by Regulating P-Glycoprotein in Multi-Drug Resistant Cancer Cells
por: Teng, Yu-Ning, et al.
Publicado: (2019)

Immunomodulatory Effects of Fruiting Body Extract and Solid-State-Cultivated Mycelia of Taiwanofungus camphoratus
por: Lin, Liang-Hung, et al.
Publicado: (2019)

Effects of Taiwanofungus camphoratus on non-specific and specific immune activities in mice
por: Chen, Yun-Yu, et al.
Publicado: (2018)

The Regulatory Effects of a Formulation of Cinnamomum osmophloeum Kaneh and Taiwanofungus camphoratus on Metabolic Syndrome and the Gut Microbiome
por: Wang, Ya-Yun, et al.
Publicado: (2020)

Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells
por: Lai, I-Chun, et al.
Publicado: (2017)

Molecular cloning and characterization of a thioredoxin from Taiwanofungus camphorata
por: Chen, Yu-Ting, et al.
Publicado: (2014)

Application of Lanthanide Shift Reagent to the (1)H-NMR Assignments of Acridone Alkaloids
por: Lam, Sio-Hong, et al.
Publicado: (2020)

Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer
por: Marginean, Esmeralda C., et al.
Publicado: (2020)

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent
por: Ball, Daniel P., et al.
Publicado: (2016)

Urocortin Induces Phosphorylation of Distinct Residues of Signal Transducer and Activator of Transcription 3 (STAT3) via Different Signaling Pathways
por: Corsetti, Giovanni, et al.
Publicado: (2019)

Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity
por: Wu, Chin-Jui, et al.
Publicado: (2019)

Fermented Taiwanofungus camphoratus Extract Ameliorates Psoriasis-Associated Response in HaCaT Cells via Modulating NF-𝜅B and mTOR Pathways
por: Shen, Jia-Wei, et al.
Publicado: (2022)

Biochemical characterization of a functional recombinant aryl-alcohol dehydrogenase from Taiwanofungus camphorata
por: Ken, Chuian-Fu, et al.
Publicado: (2014)

Combination of cut-log cultivated fruiting body and solid-state cultured mycelia of Taiwanofungus camphoratus ameliorates CCl(4)-induced liver injury in rats
por: Lu, Kuan-Hung, et al.
Publicado: (2019)

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
Publicado: (1995)

8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells
por: Wu, Pei-Shan, et al.
Publicado: (2021)

Raf Kinase Inhibitor Protein (RKIP) Blocks Signal Transducer and Activator of Transcription 3 (STAT3) Activation in Breast and Prostate Cancer
por: Yousuf, Saad, et al.
Publicado: (2014)

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia
por: Przanowski, Piotr, et al.
Publicado: (2013)

Bioassay-guided purification of sesquiterpenoids from the fruiting bodies of Fomitopsis pinicola and their anti-inflammatory activity
por: Tai, Shih-Huang, et al.
Publicado: (2019)

3,3'-Diindolylmethane Inhibits Flt3L/GM-CSF-induced-bone Marrow-derived CD103(+) Dendritic Cell Differentiation Regulating Phosphorylation of STAT3 and STAT5
por: Park, Joo-Hung, et al.
Publicado: (2015)

The complete mitochondrial genome of medicinal fungus Taiwanofungus camphoratus reveals gene rearrangements and intron dynamics of Polyporales
por: Wang, Xu, et al.
Publicado: (2020)

Danazol mediates collateral sensitivity via STAT3/Myc related pathway in multidrug-resistant cancer cells
por: Chang, Ying-Tzu, et al.
Publicado: (2019)

EGFR-mediated tumor immunoescape: The imbalance between phosphorylated STAT1 and phosphorylated STAT3
por: Concha-Benavente, Fernando, et al.
Publicado: (2013)

Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
por: Madani, Aisha Y., et al.
Publicado: (2021)

Analysis of Radiation Toxicity in Mammalian Cells Stably Transduced with Mitochondrial Stat3
por: Zanin, Alisa, et al.
Publicado: (2023)

Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells
por: Patel, Amit K, et al.
Publicado: (2013)

Signal transducer and activator of transcription 3 (STAT3) promoter methylation and expression in pituitary adenoma
por: Valiulyte, Indre, et al.
Publicado: (2017)

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication
por: Loh, Chin-Yap, et al.
Publicado: (2019)

Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3
por: Yu, Xiaokui, et al.
Publicado: (2015)

Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
por: Lam, Sio-Hong, et al.
Publicado: (2018)

Chemical Constituents of Hedyotis diffusa and Their Anti-Inflammatory Bioactivities
por: Hung, Hsin-Yi, et al.
Publicado: (2022)

Treating hepatocellular carcinoma with (90)Y-bearing microspheres: a review
por: Hsieh, Te-Chun, et al.
Publicado: (2016)

STAT3 phosphorylation in central leptin resistance
por: Liu, Huimin, et al.
Publicado: (2021)

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
por: Arora, Loukik, et al.
Publicado: (2018)

Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors
por: Furtek, Steffanie L., et al.
Publicado: (2016)

Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
por: Wu, Song, et al.
Publicado: (2018)

A Modified (1)H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples
por: Li, Yue-Chiun, et al.
Publicado: (2023)

Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)
por: Yun, Sun, et al.
Publicado: (2021)

Laricitrin ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal transducer and activator of transcription 3
por: Chang, Wei-An, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d0t9hmue61r53i54huqjl0ftfh