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Novel c-Jun N-Terminal Kinase (JNK) Inhibitors with an 11H-Indeno[1,2-b]quinoxalin-11-one Scaffold
c-Jun N-terminal kinase (JNK) plays a central role in stress signaling pathways implicated in important pathological processes, including rheumatoid arthritis and ischemia-reperfusion injury. Therefore, inhibition of JNK is of interest for molecular targeted therapy to treat various diseases. We syn...
Autores principales: | Liakhov, Serhii A., Schepetkin, Igor A., Karpenko, Olexander S., Duma, Hanna I., Haidarzhy, Nadiia M., Kirpotina, Liliya N., Kovrizhina, Anastasia R., Khlebnikov, Andrei I., Bagryanskaya, Irina Y., Quinn, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464905/ https://www.ncbi.nlm.nih.gov/pubmed/34577159 http://dx.doi.org/10.3390/molecules26185688 |
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