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Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia

Previous studies on lengthening for achondroplasia have reported bilateral extensive femoral lengthening followed by bilateral extensive tibial lengthening. To decrease trauma on soft tissues and joints, we propose bilateral simultaneous moderate femoral lengthening and moderate tibial lengthening f...

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Autores principales: Shabtai, Lior, Jauregui, Julio J., Herzenberg, John E., Gesheff, Martin G., Standard, Shawn C., McClure, Philip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465182/
https://www.ncbi.nlm.nih.gov/pubmed/34572181
http://dx.doi.org/10.3390/children8090749
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author Shabtai, Lior
Jauregui, Julio J.
Herzenberg, John E.
Gesheff, Martin G.
Standard, Shawn C.
McClure, Philip K.
author_facet Shabtai, Lior
Jauregui, Julio J.
Herzenberg, John E.
Gesheff, Martin G.
Standard, Shawn C.
McClure, Philip K.
author_sort Shabtai, Lior
collection PubMed
description Previous studies on lengthening for achondroplasia have reported bilateral extensive femoral lengthening followed by bilateral extensive tibial lengthening. To decrease trauma on soft tissues and joints, we propose bilateral simultaneous moderate femoral lengthening and moderate tibial lengthening followed by a similar repeat lengthening a few years later. Fifty patients with achondroplasia underwent 65 simultaneous bilateral femoral and tibial lengthening procedures. Segment lengthening amount and adverse events were obtained from medical records. Mean follow-up after bone healing was 35.6 months. Mean tibial lengthening was 52 mm; mean femoral lengthening was 72 mm. Average healing index was 1.4 months/cm for the tibia and 1 month/cm for the femur. Mean duration of treatment with external fixation was 6.7 months (range, 4.4–10.5 months). Thirty-eight (76%) of 50 patients experienced one or more adverse events during lengthening. We observed 78 adverse events, 35 (45%) of which required additional surgical procedures. All resolved by the end of treatment. Mechanical axis deviation improved from a mean of 15 mm medially to 8 mm medially. Simultaneous lengthening of four segments in patients with achondroplasia is a feasible strategy. Compared with isolated femoral or tibial lengthening, distributing the lengthening between the femur and tibia decreases total external fixator time.
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spelling pubmed-84651822021-09-27 Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia Shabtai, Lior Jauregui, Julio J. Herzenberg, John E. Gesheff, Martin G. Standard, Shawn C. McClure, Philip K. Children (Basel) Article Previous studies on lengthening for achondroplasia have reported bilateral extensive femoral lengthening followed by bilateral extensive tibial lengthening. To decrease trauma on soft tissues and joints, we propose bilateral simultaneous moderate femoral lengthening and moderate tibial lengthening followed by a similar repeat lengthening a few years later. Fifty patients with achondroplasia underwent 65 simultaneous bilateral femoral and tibial lengthening procedures. Segment lengthening amount and adverse events were obtained from medical records. Mean follow-up after bone healing was 35.6 months. Mean tibial lengthening was 52 mm; mean femoral lengthening was 72 mm. Average healing index was 1.4 months/cm for the tibia and 1 month/cm for the femur. Mean duration of treatment with external fixation was 6.7 months (range, 4.4–10.5 months). Thirty-eight (76%) of 50 patients experienced one or more adverse events during lengthening. We observed 78 adverse events, 35 (45%) of which required additional surgical procedures. All resolved by the end of treatment. Mechanical axis deviation improved from a mean of 15 mm medially to 8 mm medially. Simultaneous lengthening of four segments in patients with achondroplasia is a feasible strategy. Compared with isolated femoral or tibial lengthening, distributing the lengthening between the femur and tibia decreases total external fixator time. MDPI 2021-08-30 /pmc/articles/PMC8465182/ /pubmed/34572181 http://dx.doi.org/10.3390/children8090749 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shabtai, Lior
Jauregui, Julio J.
Herzenberg, John E.
Gesheff, Martin G.
Standard, Shawn C.
McClure, Philip K.
Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title_full Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title_fullStr Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title_full_unstemmed Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title_short Simultaneous Bilateral Femoral and Tibial Lengthening in Achondroplasia
title_sort simultaneous bilateral femoral and tibial lengthening in achondroplasia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465182/
https://www.ncbi.nlm.nih.gov/pubmed/34572181
http://dx.doi.org/10.3390/children8090749
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