Aggregation of Cystatin C Changes Its Inhibitory Functions on Protease Activities and Amyloid β Fibril Formation

Cystatin C (CST3) is an endogenous cysteine protease inhibitor, which is implicated in cerebral amyloid angiopathy (CAA). In CAA, CST3 is found to be aggregated. The purpose of this study is to investigate whether this aggregation could alter the activity of the protein relevant to the molecular pat...

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Detalles Bibliográficos
Autores principales: Sheikh, Abdullah Md., Wada, Yasuko, Tabassum, Shatera, Inagaki, Satoshi, Mitaki, Shingo, Yano, Shozo, Nagai, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465189/
https://www.ncbi.nlm.nih.gov/pubmed/34575849
http://dx.doi.org/10.3390/ijms22189682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465189/
https://www.ncbi.nlm.nih.gov/pubmed/34575849
http://dx.doi.org/10.3390/ijms22189682

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