SVCT2 Overexpression and Ascorbic Acid Uptake Increase Cortical Neuron Differentiation, Which Is Dependent on Vitamin C Recycling between Neurons and Astrocytes

During brain development, sodium–vitamin C transporter (SVCT2) has been detected primarily in radial glial cells in situ, with low-to-absent expression in cerebral cortex neuroblasts. However, strong SVCT2 expression is observed during the first postnatal days, resulting in increased intracellular c...

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Detalles Bibliográficos
Autores principales: Salazar, Katterine, Espinoza, Francisca, Cerda-Gallardo, Gustavo, Ferrada, Luciano, Magdalena, Rocío, Ramírez, Eder, Ulloa, Viviana, Saldivia, Natalia, Troncoso, Ninoschka, Oviedo, María José, Barahona, María José, Martínez, Fernando, Nualart, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465431/
https://www.ncbi.nlm.nih.gov/pubmed/34573045
http://dx.doi.org/10.3390/antiox10091413

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