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CYP3A Activity in End-of-Life Cancer Patients Measured by 4β-Hydroxycholesterol/cholesterol Ratio, in Men and Women

SIMPLE SUMMARY: The elimination of drugs by enzymes in the liver may be impaired in cancer patients that are close to death (end-of-life). This could cause unwanted side effects or lack of effect of drugs and compromise the quality of life in patients. Blood samples collected in 137 deceased end-of-...

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Detalles Bibliográficos
Autores principales: Bergström, Helena, Helde Frankling, Maria, Klasson, Caritha, Lövgren Sandblom, Anita, Diczfalusy, Ulf, Björkhem-Bergman, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465465/
https://www.ncbi.nlm.nih.gov/pubmed/34572915
http://dx.doi.org/10.3390/cancers13184689